Research

Let no pandemic go to waste: How the COVID crisis could lead to better health care delivery

The COVID-19 pandemic is forcing us to re-organize and re-conceptualize many aspects of our lives.  In this Grand Round, I will start with some general thoughts about these changes.  Then, I will focus specifically on the challenges that the pandemic creates for the way that we oversee and regulate clinical research.   I will speculate about whether some of these changes represent a better way of doing things and thus ought to change the way we practice after the pandemic. 

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COVID-19: Spotlight on Schools and Kids in Melbourne

It is well established that kids get less sick from COVID-19 than adults. However, what do we know about the extent infected children contribute to spreading the virus?
With some areas of Melbourne approaching their third week of lockdown and widespread community transmission, how do we make decisions about when it’s safe to reopen schools and what can we do to prevent kids from transmitting the virus? At Melbourne’s largest children’s hospital, we will hear what the commonest conditions are that are causing kids to get sick during the COVID-19 pandemic.

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What’s COVID-19 doing to our blood vessels?

Blood-clotting complications are rapidly emerging as a significant part of the pathogenesis of COVID-19. There are reports of otherwise well people with COVID-10 having strokes, pulmonary emboli and heart attacks, and children with inflammation of their blood vessels. In recent weeks series of cases of a multi-system inflammatory condition, some resembling Kawasaki disease, have been reported in children in Europe, UK and USA.

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COVID-19: Are the Kids Really OK?

Data from around the world consistently shows that COVID-19 is essentially a mild disease in children. However, the indirect effects of COVID-19 may have a more profound effect than the direct effects of the infection.
We will hear from 3 speakers on the global and clinical aspects, and the broader social, education and wellbeing impact of COVID-19 on children.

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Endeavoring to preserve fertility for children undergoing cancer treatment – current evidence, current debate 

Today, 80% of children treated for cancer will survive. However, a significant proportion of survivors are at risk of infertility, due to toxicity of their treatment. The Royal Children’s Hospital is a leader worldwide in promoting discussion of fertility issues at the time of treatment, and offering options that might be able to preserve fertility for the future.

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Neonatal Seizures: To fit or not to fit?

Seizures are more common in the neonatal period than at any other time of life. Recognition of seizures in the NICU has changed in recent years with the introduction of bedside EEG tools. Increased recognition has raised the sceptre of whether all subclinical seizures need treatment with anticonvulsants.

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Generation Victoria (GenV) Solving complex issues affecting children and adults – a whole-of-state cohort with whole-of-campus implications

GenV’s vision is to help solve complex issues affecting today’s children and adults through an entire Australian state becoming a single platform that enhances research speed, capacity and translation. Led from the Melbourne Children’s Campus, the GenV Cohort will be open to the families of all 170,000 Victorian newborns over 2021-2. At its foundation are consent; existing geospatial, clinical and administrative data; biosamples; GenV-specific data; and melding observational and intervention design

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