Genetic conditions are the leading cause of death in children in high-income countries. Accurate and timely diagnosis is critical for being able to provide prognostic information and guide treatment, yet often takes many years.
Sophie Deane is a 20-year-old young woman with some pretty big ideas about what she would like to do with her life. She has just finished school and is keen to get on and find a job, move out of home, travel – and maybe even get married. She would like the chance to tell you more about those hopes and dreams.
Medulloblastoma is the most common malignant brain tumour of childhood. Despite multidisciplinary therapies offered by neurosurgery, radiation oncology and paediatric oncology through cooperative group clinical trials, there are significant late effects of therapy, including but not limited to neuroendocrine deficits, neurocognitive impairment and second malignant neoplasms
Hospitalisation for treatment of serious illness can place infants, and their families, at risk with respect to their mental health. Trauma responses are common, and optimal infant-parent relationship development may be disrupted. Significant additional environmental and psychosocial burdens were placed on this group in 2020 as a consequence of measures adopted to protect the community from COVID-19.
Neuroscience Advanced Clinical Imaging Service (NACIS) is the translational clinical and research program embedded in the Neurosurgery Department at The Royal Children’s Hospital (RCH). Although officially established in January 2020, NACIS emerged from work since 2012 which was supported by a Clinical Paediatric Neurosurgery Research Fellowship from the RCH Foundation.
The WHO’s World Hearing Day theme on 3rd March 2021 is ‘Hearing care for all: screen, rehabilitate, communicate’. The Royal Children’s Hospital is home to the Victorian Infant Hearing Screening Program (VIHSP) that has been delivering world-class universal hearing screening to Victorian babies for over a decade. Beyond screening, the RCH Audiology Clinic provides diagnostic care, and the Caring for Hearing Impaired Children (CHIC) Clinic delivers a multidisciplinary medical service that intersects with external audiology and early intervention services for hearing-impaired children beyond the hospital. Both VIHSP and CHIC are integrated with a childhood hearing loss research program at the Murdoch Children’s Research Institute to ensure evidence from research informs delivery of the best clinical care.
The Kidney Flagship is an RCH Foundation funded project which aims to reduce the burden of genetic kidney disease on patients and their families by improving diagnosis, treatment and developing new targeted therapies. In this Grand Rounds we will show how our work has already impacted on the care of children with kidney disease and our plans for the future.
Never in the field of health was so much learned by so many in so few months. This, the opening Grand Round for 2021 will recap the lessons from last year, take stock of where we are in February 2021, describe the complex situation with vaccines, and look to what the year might hold for the pandemic and children in Australia and countries around the world. Topics will include: Why is COVID-19 less severe in children? What is the role of schools in transmission and what is the impact of new variants? Vaccines: who, when and how? The indirect effects of Covid: poverty and malnutrition, measles, loss of education, and child marriage.
recision (or personalised) Health is being promoted as the future of healthcare. Indeed, precision health is the key theme of the latest MCRI strategic plan and the focus of much attention on campus. One of the key tools in precision health is genomics. During this Grand Round, Prof Colin Robertson will reflect on his extensive experience as a clinician-scientist in paediatric respiratory medicine. In particular, he will focus on the successes and failures of genomics in conditions such as cystic fibrosis and asthma, and he will contend that the key to using genomics to improve patient care is a strong understanding of physiology in health and disease.
For several months, we have experienced significant restrictions on how we live and work. Whilst Victoria’s strict lockdown protocols are working to suppress the virus, for many of us, social isolation has taken a toll on mental health. Our new reality, and the social, mental and emotional deprivation that accompanies it, highlights that what we do in life and who we do it with, are critical to how we feel.
