Research

Precision Health in paediatric respiratory medicine – physiology is the key

recision (or personalised) Health is being promoted as the future of healthcare. Indeed, precision health is the key theme of the latest MCRI strategic plan and the focus of much attention on campus. One of the key tools in precision health is genomics. During this Grand Round, Prof Colin Robertson will reflect on his extensive experience as a clinician-scientist in paediatric respiratory medicine. In particular, he will focus on the successes and failures of genomics in conditions such as cystic fibrosis and asthma, and he will contend that the key to using genomics to improve patient care is a strong understanding of physiology in health and disease.

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Busting the Superhero Myth – Our Mental Health during a pandemic

For several months, we have experienced significant restrictions on how we live and work. Whilst Victoria’s strict lockdown protocols are working to suppress the virus, for many of us, social isolation has taken a toll on mental health.  Our new reality, and the social, mental and emotional deprivation that accompanies it, highlights that what we do in life and who we do it with, are critical to how we feel.   

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Let no pandemic go to waste: How the COVID crisis could lead to better health care delivery

The COVID-19 pandemic is forcing us to re-organize and re-conceptualize many aspects of our lives.  In this Grand Round, I will start with some general thoughts about these changes.  Then, I will focus specifically on the challenges that the pandemic creates for the way that we oversee and regulate clinical research.   I will speculate about whether some of these changes represent a better way of doing things and thus ought to change the way we practice after the pandemic. 

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COVID-19: Spotlight on Schools and Kids in Melbourne

It is well established that kids get less sick from COVID-19 than adults. However, what do we know about the extent infected children contribute to spreading the virus?
With some areas of Melbourne approaching their third week of lockdown and widespread community transmission, how do we make decisions about when it’s safe to reopen schools and what can we do to prevent kids from transmitting the virus? At Melbourne’s largest children’s hospital, we will hear what the commonest conditions are that are causing kids to get sick during the COVID-19 pandemic.

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What’s COVID-19 doing to our blood vessels?

Blood-clotting complications are rapidly emerging as a significant part of the pathogenesis of COVID-19. There are reports of otherwise well people with COVID-10 having strokes, pulmonary emboli and heart attacks, and children with inflammation of their blood vessels. In recent weeks series of cases of a multi-system inflammatory condition, some resembling Kawasaki disease, have been reported in children in Europe, UK and USA.

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COVID-19: Are the Kids Really OK?

Data from around the world consistently shows that COVID-19 is essentially a mild disease in children. However, the indirect effects of COVID-19 may have a more profound effect than the direct effects of the infection.
We will hear from 3 speakers on the global and clinical aspects, and the broader social, education and wellbeing impact of COVID-19 on children.

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Endeavoring to preserve fertility for children undergoing cancer treatment – current evidence, current debate 

Today, 80% of children treated for cancer will survive. However, a significant proportion of survivors are at risk of infertility, due to toxicity of their treatment. The Royal Children’s Hospital is a leader worldwide in promoting discussion of fertility issues at the time of treatment, and offering options that might be able to preserve fertility for the future.

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Neonatal Seizures: To fit or not to fit?

Seizures are more common in the neonatal period than at any other time of life. Recognition of seizures in the NICU has changed in recent years with the introduction of bedside EEG tools. Increased recognition has raised the sceptre of whether all subclinical seizures need treatment with anticonvulsants.

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