Genetic epilepsies and precision medicine

This Grand Round, presented by Dr Annapurna Poduri from Boston will explore the role of genetics in epilepsy and the importance of pursuing genetic diagnoses in patients with epilepsy as a step toward refined treatment and precision medicine strategies. Dr Puduri will emphasize the importance of integrating what we know from the clinic into clinically relevant model systems.

A child’s right to know – how far does it extend?

The child’s right to know is usually raised in discussions about whether a child should be given information about their medical condition – what it is, what treatment is proposed, what the outlook is long-term. The standard ethical position and usual clinical practice, is that children should receive developmentally appropriate information. Even on this matter, there are noticeable differences about what information is appropriate at what stage, and what counts as a sound reason to give that information

Human Papilloma Virus, epidemiology and immunization in Victoria and the Pacific: implications for paediatricians

In this Grand Round Yasmin will discuss the evolution of our understanding of HPV and cervical cancers through the lens of a paediatric and adolescent gynaecologist. With the planned transition to later onset of cervical screening at 25 years with HPV DNA testing, she launched The Early-Onset Cervical Cancer Study Group in 2007, examining pre-vaccination virology, and cancer morphology, shedding light on predicted impact of HPV vaccination in those under 25 years.
Professor Fiona Russell and her team undertook cervical cancer epidemiology in Fiji and reviewed the cervical cancer screening program to enable the Fiji Ministry of Health to make an evidence-based decision on the introduction of HPV vaccine into the national immunisation schedule.

Fearless, Tearless Transition: Improving long term outcomes for young people with Intellectual Disability or Autism Spectrum Disorder with mental health concerns and their families

Optimising the care and management of patients with behaviours of concern is a key priority for the Royal Children’s Hospital. Several departments have now embedded a new model of care introduced in 2016 for adolescents with an intellectual disability and or Autism Spectrum Disorder with mental health concerns. At this Grand Round, we will hear from a parent, a GP and clinicians who will provide insights into the challenges and progress of this important initiative.

Neurons and growth factors: The good, the bad and the future

The Insulin-like Growth Factor (IGF) system plays a fundamental role throughout the life cycle, acting via both endocrine and paracrine mechanisms. Studies by Prof George Werther and the Endocrine Research team at the Melbourne Children’s Campus have shown that IGF is critical in early development, especially in the brain, where a deficiency leads to marked microcephaly, and it is essential in repair of ischaemic injury.

Today’s patients are tomorrow’s workforce: Building a future for children with disability

How can we build the hopes and aspirations of patients living with or likely to experience disability? We show them a society where people with disability are already making meaningful contributions in the workforce. The Health and Social Assistance industry is Victoria’s largest and fastest growing employing industry, yet people with disability are significantly underrepresented.

Burnout, clinician wellbeing, and keeping the humanity in health care

There has been an increasing awareness and discussion about burnout in clinicians – but what does this mean, who is affected and what can we do about it? The humanity in healthcare is at the heart of what we do in paediatrics, yet sometimes modern medical care can get in the way of this. We believe it is essential to nurture a culture of kindness throughout the healthcare system.

Following the evidence to build safe families

OzChild is a Government funded organisation for the care of vulnerable families.  It is a direct descendent of one of the earliest orphanages in Melbourne, the St James’ Dorcas Society shelter for orphaned children.  Today it is a national organisation and all their work is done in community and homes, working with families.
OzChild’s vision is that ‘All children and young people are safe, respected, nurtured and reach their full potential’. As part of its strategic plan 2016-2020 it aims to measure the impact and success of its programs using a strong evidence-based methodology and reporting of client outcomes.