Both RSV and Dengue have proved to be difficult vaccine targets. In both cases vaccine development has taken a very long time, and in both cases some vaccine candidates have led to more severe disease in some individuals. We are currently in the middle of an era of remarkable progress in both fields, but problems remain.
In today’s Grand Round Dr Tom Forbes will discuss primary hyperoxaluria (PH), an ultra-rare and often devastating kidney-stone forming disease which can lead to recurrent kidney stones and end-stage kidney disease.
This Grand Round will provide a critical overview of what we know about holding children for clinical procedures, considering the child, parent, health professional and system factors which can influence procedural practice. Lucy will discuss an approach to challenge accepted narratives within practice and adopt a more child-centred rights-based approach to reduce harm and the use of restrictive practice during procedures.
One hundred years ago the first insulin injection was given at RCH. Overnight, type 1 diabetes went from a fatal to a ‘manageable’ condition. Since that time, diabetes management has developed and evolved to a point where in the near future it is hoped that exogenous insulin will represent a treatment failure rather than a therapeutic mainstay. This Grand Round will trace the history of insulin therapy and diabetes management at RCH, and discuss the likely direction of new therapies in the upcoming decades.
After completing a comprehensive process, including stakeholder engagement and workshops, the Murdoch Children’s Research Institute has established a Cancer Flagship to bring together child health researchers across multiple disciplines interested and invested in childhood cancer across the research continuum.
The Grand Rounds will explore:
Bringing the voice of the child and family into our day-to-day interactions, and the importance of lived experience perspectives when designing new approaches to support mental health and wellbeing.
The independent Consultative Council on Obstetric and Paediatric Mortality and Morbidity (CCOPMM) reviews cases of maternal, perinatal, and paediatric mortality and morbidity. Child deaths have been reviewed since 1985. The child and adolescent subcommittee of CCOPMM reviews deaths and develops recommendations and good practice points for practitioners and health systems.
Multi-disciplinary care is vital for the treatment of complex patients, especially those with rare diseases. The benefits of multi-disciplinary collaboration go beyond clinical outcomes and include research.
This year’s NAIDOC Week Theme, ‘For Our Elders’ celebrates the valuable contribution of Aboriginal and Torres Strait Islander Elders in all areas of Australia. Please join Melbourne Children’s Campus leaders in Aboriginal and Torres Islander healthcare in a panel discussion about the crucial role that Elders play in our services, programs, care and research. The panel aims to acknowledge and celebrate the often hidden guidance, influence and advocacy of Elders in health.
Meta-analyses show that medication is an effective treatment pathway in children and adolescents diagnosed with ADHD. These medications are also commonly associated with a number of side effects and risk factors for other conditions, which are less well understood by practitioners. This Grand Round intends to balance understanding of the efficacy of ADHD medication with the potential risks, and provide evidence for the safety of ADHD medication prescription in clinical practice.
