Global Health

An evidence-based system for early years interventions to reduce child health and developmental inequities: Insights from the interventional birth cohort study Born in Bradford’s Better Start (BiBBS)

There are real challenges in delivering equitable health care in a community, even when there is policy and service goodwill. This is an issue for health services around the world. For the past ten years BiBBS has been working alongside service partners and families to co-design, implement and evaluate multiple early years interventions that are delivered as a part of usual practice in disadvantaged inner-city areas in the UK.

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Localising efforts to improve care for children in a global world, to reach those in greatest need

Globally, we face many common challenges. Yet how do we address these in different health contexts to ensure that the right care reaches those who need it the most, in the right way? Decentralisation, localisation, “glocalisation”…many labels been applied to approaches, and debate ensues about which approach is “right”. Yet the aim is common – best care, best outcomes, everywhere. 

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The Centre for Adolescent Health: Supporting the healthy development of young people

Spanning the three campus partners, the Centre for the Adolescent Health has driven actions for adolescent health over more than 3 decades, with the aim of understanding and promoting the healthy development of young people, locally and globally. Newly appointed as a Professor of Adolescent Health, Professor Peter Azzopardi will share his personal journey in adolescent health, and in doing so will celebrate the legacy of the late Professor George Patton. 

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Difficult vaccine targets – RSV and Dengue

Both RSV and Dengue have proved to be difficult vaccine targets.  In both cases vaccine development has taken a very long time, and in both cases some vaccine candidates have led to more severe disease in some individuals. We are currently in the middle of an era of remarkable progress in both fields, but problems remain. 

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reNEW: Transforming lives with stem cell medicine

Scientific advances now allow researchers to identify, isolate and engineer stem cells. reNEW aims to deliver treatment outcomes across the breadth of stem cell medicine – new drugs based on human stem cell models, new tissue therapies, and new cell and gene therapies. We look forward to presenting how stem cell medicine and reNEW are advancing treatments for delivery into the clinic across many currently untreatable diseases.

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30 years of Musculoskeletal Research in Cerebral Palsy: From Melbourne to Basel and Boston (and back!)

In three parts, this Grand Round intends to describe the significant developments in the management of musculoskeletal conditions associated with cerebral palsy. First, the critical role that the Victorian Cerebral Palsy Register (VCPR) has played in epidemiological research, clinical research, and public health policy will be outlined. The second section will discuss technical developments in the management of Neuromuscular Hip Dysplasia, including novel imaging techniques and new aids for surgeons when considering surgical treatment. The final section will focus on common gait problems in children with cerebral palsy, as well as novel treatment concepts

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Caring for Children with Cancer Wherever They May Live: ARIA and the Global Initiative for Childhood Cancer

Is it possible, and is it ethical to resource-adapt cancer treatment developed in high income countries for the benefit of children with cancer living in low- and middle-income settings?

This is the dilemma, and the challenge, faced by health care professionals in such countries who care for 80% of the world’s children who have cancer, and where the chance of cure often remains poor. Adapting cancer treatment is a key pillar of the WHO Global Initiative for Childhood Cancer to improve the cure rates for children with cancer to 60% by 2030.

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Learning Health Systems

The term ‘learning health systems’ is not new. But widespread consensus that learning is crucial for health system performance is not matched by shared understanding of how health systems learn. The speaker will present ideas for such shared understanding based on a recent report by the WHO’s Alliance for Health Policy and Systems Research.

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COVID-19: An Update: What have we learnt over the last 12 months?

Never in the field of health was so much learned by so many in so few months. This Grand Round will recap the lessons from last year, take stock of where we are in February 2022, describe the complex situation with vaccines, and look to what the year might hold for the pandemic and children in Australia and countries around the world. 

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The pathogens causing child pneumonia: An ever-changing spectrum

It is World Pneumonia Day on November 12th. Pneumonia remains a leading cause of death among young children despite the widespread introduction of pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b (Hib) vaccine. Respiratory syncytial virus (RSV) is a common respiratory virus that may cause severe respiratory disease especially in infants. We will describe the findings of a systematic review, which was part of a series for WHO, which aimed to determine the common aetiology of severe and non-severe community acquired pneumonia among children 1 month to 9 years of age in low- and middle-income countries globally. We will also discuss the impact of the global pandemic on the epidemiology of respiratory infections with a focus on RSV.

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