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Synopsis:Intravenous fluid are widely used in hospitalised children, however the evidence underpinning the choice of fluid for maintenance IV hydration has been lacking. Adverse events in many countries, some quite serious or fatal, have led to widespread uncertainty regarding the ideal IV fluid for sick children. The PIMS (Paediatric Intravenous Maintenance Solution) study, performed at RCH in collaboration with The University of Melbourne and Murdoch Childrens Research Institute, was the largest randomised controlled trial ever done on this campus. This research involved patients and staff from most clinical departments and wards. You’ll get to hear the study results for the first time, and we’ll discuss the implications for how we treat children, and the challenges in conducting big clinical trials.

Speaker: Dr Sarah McNab is a general paediatrician at the Royal Children’s Hospital and was the lead investigator for the PIMS study. She is currently completing a PhD through the University of Melbourne and MCRI.