The Human Neonatal Rotavirus Vaccine (RV3-BB) Targeting Rotavirus from Birth: from discovery to the development of a vaccine for the world’s children
Rotavirus is a major cause of death and disease in children worldwide. Despite clear evidence of the success of rotavirus vaccines, barriers remain to global implementation with over 94 million children still lacking access to a rotavirus vaccine. These barriers include sub-optimal efficacy in low-income settings, lingering safety concerns and cost. Administering a vaccine at birth has the potential to address these challenges.