Updated CPG: Sodium valproate poisoning

The Sodium valproate poisoning CPG has been updated by the Toxicology Committee and reviewed by interstate reviewers.


The Key points for the CPG are

  1. Toxicity is dose-dependent and serious symptoms are unlikely with ingestions <400 mg/kg
  2. Sodium valproate concentrations and an ECG can be helpful in assessment
  3. Early consideration of transfer to a tertiary centre due to need for intensive care support (eg Enhanced elimination with haemodialysis)


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