The Nitrous oxide – oxygen mix CPG has been updated and reviewed by the CPG committee.

This CPG forms part of a suite of CPGs relating to sedation, other new topics are Procedural sedation and Ketamine use for procedural sedation

The Key points for the CPG are

1. Nitrous oxide provides amnesia, anxiolysis and modest analgesia with minimal respiratory and cardiovascular compromise
2. Nitrous is safe to commence at a concentration of 70%. There is no evidence to support gradual weaning of nitrous oxide concentration
3. Administration of nitrous for more than 30 minutes is more likely to result in side effects such as vomiting