The Non-IgE mediated food allergy CPG is a new CPG developed in conjunction with Allergy specialists, together with the CPG Committee and endorsed by the Paediatric Improvement Collaborative (December 2022). This CPG provides a comprehensive overview of the approach to diagnosis and management of non-IgE-mediated food allergies in children, including Food Protein-Induced Allergic Proctocolitis and Food Protein-Induced Enteropathy (which relate to the condition still commonly known to many clinicians as CMPI), and FPIES.
CPG key points
- Non-IgE-mediated food allergies are delayed immune-mediated reactions to food
- Non-IgE-mediated allergies are diagnosed on the basis of clinical history and do not require allergy testing
- Treatment is based on elimination of the trigger food(s), there is no need for adrenaline or antihistamines
- FPIES can lead to dehydration and shock, and may need acute treatment
This CPG adds to the suite of guidelines for Food Allergy in children. See also IgE-mediated food allergy