Paediatric upper limb transplantation: A new frontier of surgery, immunology, and ethics
Hand transplantation is a technique to reconstruct absent and functionless upper limbs using cadaveric donor limbs.
In the 20 years since the world’s first hand transplant, the technique has developed into a reliable and valuable option for carefully selected adult amputees. The downside is the need for immunosuppression with its inherent risks (metabolic, infective, neoplastic, and renal impairment) for the duration of the transplant.