The Bacille Calmette-Guérin (BCG) vaccine, a 100-year-old vaccine usually given to protect against tuberculosis, also has ‘off-target’ effects on the immune system that protect against other infections and allergic diseases.
Racism as a fundamental cause of health and health inequalities is increasingly recognised as a major public health crisis, echoing what First Nations peoples have been saying since colonisation. There is growing empirical evidence of the multiple ways in which racism impacts health and wellbeing for children and young people.
Is it possible, and is it ethical to resource-adapt cancer treatment developed in high income countries for the benefit of children with cancer living in low- and middle-income settings?
This is the dilemma, and the challenge, faced by health care professionals in such countries who care for 80% of the world’s children who have cancer, and where the chance of cure often remains poor. Adapting cancer treatment is a key pillar of the WHO Global Initiative for Childhood Cancer to improve the cure rates for children with cancer to 60% by 2030.
The Melbourne Children’s Campus has a strong history of academic surgical excellence. As we make strides towards enhancing surgical collaborations, we aim to create a Surgical Research Program that will encourage and support all interested surgeons and surgical trainees.
Adolescent use of violence in the home (AVITH) refers to violence, or abusive or intimidating behaviours by a young person against their parent, carer, sibling or other family member within the home. The Victorian Family Violence Reform recognises violence used by young people as a distinct form of family violence, requiring unique responses to the inherent complexities of this form of family violence. I
The primary mitochondrial oxidative phosphorylation disorders are characterized by clinical and genetic heterogeneity, limited treatment options, and poor outcomes. Part of the complexity is because both the nuclear and mitochondrial genomes may be involved. Mitochondrial DNA is maternally inherited. From a reproductive counselling perspective, couples with a family history of mitochondrial DNA disease often have limited reproductive options available to them.
Very large, truly population-representative pregnancy cohorts are rare internationally. Generation Victoria (GenV) is a whole-state cohort targeting all newborns (~150,000) and their parents over 2 full years. Components include (i) families recruited soon after birth, (ii) biospecimens from pregnancy onwards, (iii) extensive data linkage supplemented by (iv) minimal GenV collected data, all enabling (v) many additional integrated research studies, both observational and interventional.
This session will describe a 10 year initiative to develop a data and evaluation platform for children and youth mental health and service delivery in Ontario, Canada’s largest province. The session will touch on the advantages and limitations of using routinely collected health system data for surveillance and performance measurement, and challenges in evaluating a large, system wide policy strategy to improve early identification and coordination of care for children and youth with mental health disorders.
The Melbourne Children’s Campus is a global leader for longitudinal and life course data. Being one of the few centres worldwide with such extensive longitudinal cohort studies, we are positioned to address an array of questions central to early life health and development and its progression throughout the life span.
Victoria’s newborn bloodspot screening (NBS) program commenced in 1966 with screening for phenylketonuria, and from the early 1970’s close to 100% of newborns were being screened. Improvements in analytical and genetic testing technologies saw the successive introduction of screening for congenital hypothyroidism, cystic fibrosis and 22 metabolic conditions. Today, Victoria’s NBS program detects about 80 babies per year with these conditions, preventing life-long debilitating outcomes and even death.
