COVID-19: Are the Kids Really OK?

Data from around the world consistently shows that COVID-19 is essentially a mild disease in children. However, the indirect effects of COVID-19 may have a more profound effect than the direct effects of the infection.
We will hear from 3 speakers on the global and clinical aspects, and the broader social, education and wellbeing impact of COVID-19 on children.

Long-term ventilation in fatal progressive conditions: The ethics of offering, or not

The question of long-term ventilation for children with progressive conditions, such as muscular dystrophy or metabolic disease, is one of the enduring puzzles in paediatric ethics. Is it ethical to put a child on invasive mechanical ventilation when they will never be able breathe again on their own, and will inevitably die from their condition?

Now and then: The Children’s Hospital in a half century of development: Dr John Court and the development of Diabetes care, Adolescent health, and Community relationships

Several Grand Rounds in 2020, the 150th year of the Children’s Hospital, will highlight the development of services, some looking back and looking forward.  This opening Grand Round will review the innovations in diabetes, adolescent health, and links between the hospital and the community. Dr John Court was a paediatrician who had a key role in service development at The Royal Children’s Hospital from the late 1950’s to the 1990’s including research and clinical care.

Social media and health promotion: Lessons from the RCH National Child Health Poll

Social media holds considerable potential for health promotion activities, as it addresses some of the barriers in traditional methods of health communication by increasing accessibility, interaction and engagement with the community. Now in its fourth year, the RCH National Child Health Poll has evolved to increasingly use novel and innovative strategies to engage parents and carers via RCH digital channels.

Neuro-Oncology: The past, the present and the future

Neuro-Oncology had stagnated for several decades with little to no improvement in patient outcomes despite marked improvements in other areas of paediatric oncology. With the advent of advanced genomics and epigenomics and an explosion in our understanding of disease, we are finally seeing improvements. Dr Hansford will discuss the advances in modern Paediatric Neuro-Oncology and highlight the opportunities, problems and challenges as we push for better cure rates and quality of survivorship into the future for children with brain tumours.

Patient Reported Outcomes in children’s health services: why should we use them and how can they be embedded in Epic?

Patient Reported Outcomes (PRO) have been used for decades in clinical trials, observational studies, population health surveys, and for estimates of quality of life in economic evaluations. However, the use of PROs as part of routine measurement in clinical settings is relatively new.  In this Grand Round, 3 speakers will discuss the use of PROs in the UK, in mental health at RCH and integrating PROs into the EMR.

Crowd-funding and other social media use by families

One of the growing worldwide challenges in paediatric health care is how to understand and respond to some of the many ways in which families of sick children use social media. This presentation draws together a number of strands of thought from my recent sabbatical in the UK, where the paediatric hospital staff are still experiencing the flow-on effects of the high-profile (and high-conflict) social media campaigns run by parents of Charlie Gard and Alfie Evans. I will present some data from two recent studies of how families in UK and Australia use social media, especially crowd-funding, and then raise for discussion some of the ethical and social challenges arising from social media use.

Influencing global immunisation policy through research in the Asia-Pacific region

Pneumonia is the commonest cause of childhood death throughout the world, especially in low and middle income countries. The pneumococcal conjugate vaccine (PCV) has been available for 19 years, but there are still many outstanding issues in its use: how do we measure the impact of this vaccine when the causes of pneumonia are many; how do we monitor serotype replacement in the post-PCV era; how do we measure herd protection; and how many doses of the vaccine are really needed for optimal protection?

The Human Neonatal Rotavirus Vaccine (RV3-BB) Targeting Rotavirus from Birth: from discovery to the development of a vaccine for the world’s children

Rotavirus is a major cause of death and disease in children worldwide. Despite clear evidence of the success of rotavirus vaccines, barriers remain to global implementation with over 94 million children still lacking access to a rotavirus vaccine. These barriers include sub-optimal efficacy in low-income settings, lingering safety concerns and cost. Administering a vaccine at birth has the potential to address these challenges. 

What affects child development during the first 1000 days? Evidence and implications

This presentation focuses on the earliest stages of child development: the period from conception to the end of the child’s second year – known as the first 1000 days. A growing body of evidence shows that experiences during this period can have life-long consequences for health and wellbeing. The presentation is based on research for the “Strong Foundations” project and an evidence paper “Getting it right in the first 1000 days”.