Monthly Archives: December 2015

Immunotherapy for refractory leukaemia brings a new chance of cure and complex ethical issues

Acute lymphoblastic leukaemia is the most common malignancy in children. Although 5 years event-free survival rates reach 90%, some children still succumb to the disease and others achieve cure with significant late effects. Improving on this will require alternative treatments. This Grand Round will describe new options for refractory disease, and discuss some of the ethical aspects of embarking on these new treatment options.

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Early life origins of adult lung disease – a new paradigm of lung growth

Our understanding of lung growth through childhood and adolescence and the impact of disease has changed in recent years. New measurement techniques have shown alveolarisation to continue through adolescence. A number of longitudinal studies within the Campus have provided invaluable information on the outcome of childhood asthma into the adult years which, when combined with the outcome studies of extreme prematurity provide new insight into lung growth. Care of the growing lung is important to ensure optimal lung growth through childhood and adolescence to prevent early onset of lung disease in adulthood.

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